We explored how quercetin might help those suffering from heart failure. In our research, we utilized advanced databases to identify specific targets of quercetin, focusing on its effects on heart cells.
Our findings suggest that quercetin may work by reducing cell death in heart cells via the MAPK signaling pathway. Notably, it helped lower a key ratio linked to cell survival and decreased markers of cell stress. Overall, quercetin shows promise in battling heart failure symptoms, but further studies are needed to confirm these effects in broader settings.
Read More
9
Quercetin shows promise for heart recovery
Preventive Administration of Quercetin Promotes Survival and Reduces Adverse Ventricular Remodeling after myocardial infarction through facilitating M2-like macrophage polarization.
We investigated how quercetin, a natural compound found in fruits and vegetables, could help prevent damage after a heart attack (myocardial infarction). Our study used adult male mice to analyze the effects of two weeks of quercetin treatment before simulating a heart attack.
The results were encouraging: quercetin improved heart function, enhanced survival rates, and minimized heart damage. Additionally, it appeared to reduce inflammation and increase protective immune responses in the heart. Overall, quercetin shows potential as a helpful player in heart disease recovery.
Read More
9
Quercetin shows heart protection potential
Quercetin Reduces the Susceptibility to Cardiac Reperfusion Arrhythmias in Ovariectomized Rats.
We aimed to understand how quercetin, a natural flavonoid, might help protect against heart issues linked to hormonal changes in postmenopausal conditions. In our study, ovariectomized female rats received either quercetin treatment or a control substance for four weeks.
We found that quercetin significantly reduced heart damage and the risk of abnormal heart rhythms after restoration of blood flow. Additionally, it seemed to support healthier mitochondrial function. Our findings suggest that quercetin could be beneficial in managing heart health during menopause.
Read More
Most Useful Reviews
9
Powerful healing
A good supplement! Quercetin is a powerful antioxidant with significant healing effects on the body. It addresses issues like stroke and heart attack effectively. Its anti-inflammatory properties benefit blood vessels, reduce blood pressure, and protect against atherosclerosis. Additionally, its antioxidant action lowers the risk of cardiovascular disease. Quercetin exhibits strong antitumour effects and may hinder the growth of new cancer cells. I wish you all health and peace!
Read More
7.5
Supports heart health
2 people found this helpful
Life Extension Quercetin Capsules provide essential support for my health. They aid in enhancing immunity, reducing inflammation, and support heart health. I have experienced greater energy levels and reduced allergy symptoms after consistent use.
Read More
9
Effective heart protection
Quercetin exerts a myriad of beneficial effects: it is anti-inflammatory, anti-viral, anti-coagulant, and combats oxidation, while also protecting the lungs and heart. It can neutralise vital viral proteins essential for SARS-CoV-2 replication, which, when combined with vitamins and zinc, enhances its efficacy.
Preventive Administration of Quercetin Promotes Survival and Reduces Adverse Ventricular Remodeling after myocardial infarction through facilitating M2-like macrophage polarization.
We investigated how quercetin, a natural compound found in fruits and vegetables, could help prevent damage after a heart attack (myocardial infarction). Our study used adult male mice to analyze the effects of two weeks of quercetin treatment before simulating a heart attack.
The results were encouraging: quercetin improved heart function, enhanced survival rates, and minimized heart damage. Additionally, it appeared to reduce inflammation and increase protective immune responses in the heart. Overall, quercetin shows potential as a helpful player in heart disease recovery.
Read More
9
Quercetin shows heart protection potential
Quercetin Reduces the Susceptibility to Cardiac Reperfusion Arrhythmias in Ovariectomized Rats.
We aimed to understand how quercetin, a natural flavonoid, might help protect against heart issues linked to hormonal changes in postmenopausal conditions. In our study, ovariectomized female rats received either quercetin treatment or a control substance for four weeks.
We found that quercetin significantly reduced heart damage and the risk of abnormal heart rhythms after restoration of blood flow. Additionally, it seemed to support healthier mitochondrial function. Our findings suggest that quercetin could be beneficial in managing heart health during menopause.
Read More
9
Senolytics rejuvenate aging heart cells
Senolytics rejuvenate aging cardiomyopathy in human cardiac organoids.
We explored how senolytics, specifically dasatinib and quercetin, can rejuvenate aging heart muscle cells. By modeling doxorubicin-induced cardiomyopathy in human cardiac organoids, we treated these aged cells with the senolytics after they exhibited age-related damage.
Our findings showed that this treatment reduced oxidative stress and cellular damage, improving cell function and structure. Overall, senolytics were effective in restoring the viability and regenerative capabilities of these heart cells, highlighting their potential for treating age-related heart conditions.
Read More
9
Quercetin improves post-infarction outcomes
Quercetin is a potential therapy for post-infarction NETosis formation.
We explored whether quercetin could help reduce heart damage following a heart attack. In our study, Wistar rats underwent a procedure simulating a heart attack and received quercetin before the reperfusion phase. The results were encouraging—quercetin treatment improved heart function and reduced the formation of harmful substances called NETs. This suggests that quercetin may be a valuable tool for protecting the heart during recovery from cardiac events. However, our findings mainly apply to animal models and require further research in humans for validation.
Read More
9
DBD components help coronary dilation
Danggui Buxue Decoction and its components dilate coronary artery through activating the inward rectification K channels pathway.
We explored how Danggui Buxue Decoction (DBD) and its ingredients, such as quercetin, influence coronary artery dilation. By examining pre-constricted coronary arteries in a lab setting with rats, we found that the active components of DBD effectively activated potassium channels, leading to increased blood flow in the coronary arteries.
While DBD shows promise for treating conditions like coronary heart disease, more research is needed to fully understand the mechanisms behind its effects. Overall, our findings suggest it could be a beneficial therapy for those suffering from vascular issues.
A good supplement! Quercetin is a powerful antioxidant with significant healing effects on the body. It addresses issues like stroke and heart attack effectively. Its anti-inflammatory properties benefit blood vessels, reduce blood pressure, and protect against atherosclerosis. Additionally, its antioxidant action lowers the risk of cardiovascular disease. Quercetin exhibits strong antitumour effects and may hinder the growth of new cancer cells. I wish you all health and peace!
Read More
7.5
Supports heart health
2 people found this helpful
Life Extension Quercetin Capsules provide essential support for my health. They aid in enhancing immunity, reducing inflammation, and support heart health. I have experienced greater energy levels and reduced allergy symptoms after consistent use.
Read More
9
Effective heart protection
Quercetin exerts a myriad of beneficial effects: it is anti-inflammatory, anti-viral, anti-coagulant, and combats oxidation, while also protecting the lungs and heart. It can neutralise vital viral proteins essential for SARS-CoV-2 replication, which, when combined with vitamins and zinc, enhances its efficacy.
Read More
7.5
Reduces risk
Quercetin possesses robust antioxidant qualities. Numerous studies indicate that it can reduce the risk of atherosclerosis, prevent cardiovascular disease, and lower blood pressure. In this formulation, quercetin is paired with vitamin C, enhancing its effects.
Read More
7.5
Decent results
Quercetin was part of my therapy during the Covid illness and the recovery phase, alongside vitamins C, D, glutathione, resveratrol, zinc, and others. The results have been quite satisfactory!
Heart disease refers to a range of conditions that affect the heart's function and overall health. This umbrella term includes various cardiovascular issues such as coronary artery disease, which is caused by the buildup of plaque in the arteries; heart rhythm problems (arrhythmias); and heart defects present at birth (congenital heart defects). Additionally, heart disease encompasses conditions related to the heart muscle, such as cardiomyopathy, and the heart's valves, which might not open or close properly. The effects of heart disease can be significant, impacting not only physical health but also quality of life, making prevention and timely medical intervention crucial.
Several risk factors contribute to the development of heart disease, including high blood pressure, high cholesterol levels, diabetes, obesity, poor diet, physical inactivity, and smoking. Genetics also play a role, as heart disease can run in families. To mitigate the risks, healthcare professionals typically recommend lifestyle changes such as adopting a heart-healthy diet, engaging in regular physical activity, and avoiding tobacco use. For those already diagnosed with heart disease, treatment options can vary widely, ranging from lifestyle modifications to medications and, in severe cases, surgical interventions. Understanding the nature of heart disease and its risk factors is an essential step toward prevention and effective management.
Quercetin is a naturally occurring flavonoid that is found in a variety of fruits, vegetables, and grains. Known for its antioxidant properties, quercetin is believed to help combat oxidative stress in the body, which can contribute to various health issues. You can commonly find it in foods such as apples, onions, berries, and citrus fruits, as well as in leafy greens. This makes it a popular dietary supplement among health enthusiasts looking to enhance their overall wellness.
Beyond its antioxidant capacity, quercetin is also being researched for its potential anti-inflammatory effects and benefits for immune support. Some studies suggest that it may help reduce allergy symptoms and improve exercise performance by decreasing muscle fatigue. With its wide range of potential health benefits, quercetin is often marketed as a natural remedy for various ailments, although it’s essential to consult a healthcare professional before starting any new supplement regimen to ensure its safety and effectiveness for your specific needs.
Quercetin, a flavonoid found in many fruits, vegetables, and grains, has gained attention for its potential cardiovascular benefits. Studies suggest that quercetin may help improve heart health by reducing blood pressure, lowering LDL cholesterol levels, and exerting anti-inflammatory effects, which can all contribute to a healthier cardiovascular system. The antioxidant properties of quercetin may also protect blood vessels from damage, potentially reducing the risk of heart disease.
However, while the preliminary evidence is promising, more extensive clinical trials are needed to establish definitive conclusions regarding its efficacy in preventing or treating heart disease. It's essential to consider that quercetin supplements may interact with certain medications, so consulting with a healthcare professional before adding them to your regimen is advisable. A balanced diet rich in whole foods that naturally contain quercetin, such as apples, onions, and berries, remains one of the best approaches to support heart health.
Based on user reviews, many individuals have noted positive effects from taking quercetin in terms of heart health, but the timeline for observable results can vary. While some users, like one who reported a significant improvement in energy levels and reduced allergy symptoms with consistent use Read Review, do not specify an exact timeframe, it seems that regular and ongoing usage is highlighted as key to experiencing its benefits. Another user indicated that quercetin played a vital role in their recovery alongside other supplements, implying that combining it with a consistent regimen may accelerate results Read Review.
Moreover, some reviews suggest that quercetin has strong antioxidant and anti-inflammatory properties that can aid in reducing risks associated with heart disease and improving cardiovascular function over time Read Review. Overall, while specific timelines are not extensively detailed, users generally imply that maintaining a regular intake can enhance the likelihood of experiencing notable improvements in heart health.
Several studies support the potential benefits of quercetin, a natural flavonoid, in heart health. Research has demonstrated that quercetin can aid in recovery post-myocardial infarction by enhancing heart function, reducing damage, and lowering inflammation [1]. Additional findings indicate that it may also help protect against heart failure by reducing cell death in heart cells [4] and improving mitochondrial function in models representing hormonal changes linked to menopause [3]. Moreover, quercetin has shown promise in combating oxidative stress and inflammation in various heart conditions, making it a potential therapeutic agent for supporting cardiovascular health [10], [11].
Furthermore, quercetin's protective role extends to situations involving heart cell damage from factors like diabetes and oxidative stress, suggesting its versatility in treating a range of heart-related issues [13]. While the results are primarily from animal models and need further validation in human studies, the cumulative evidence indicates that quercetin may be a valuable supplement for promoting heart health and mitigating the effects of heart disease. Ongoing research continues to illuminate its efficacy and optimal applications in clinical settings.
Based on user reviews, many individuals have reported a range of improvements in their symptoms after using quercetin. Users have highlighted enhanced energy levels and a reduction in allergy symptoms after consistent use of the supplement Read Review. Quercetin's anti-inflammatory properties are frequently acknowledged, with one user mentioning its beneficial effects on heart health, including lower blood pressure and improved blood vessel function Read Review. Another review noted its importance during illness recovery, particularly in conjunction with other vitamins Read Review.
Additionally, several users report that quercetin's strong antioxidant effects contribute to an overall sense of improved well-being, by protecting against cardiovascular issues and enhancing immune response Read Review. It's also been praised for its versatility in various therapeutic areas, suggesting that while individual experiences may vary, many users found significant health benefits alongside their regular supplementation routine Read Review. Overall, while individual results may vary, user feedback underscores quercetin's potential in improving several health aspects, particularly when used consistently.
Users have reported varying experiences when combining quercetin with other supplements for managing heart disease. Several reviews highlight that pairing quercetin with vitamins C, D, and zinc, among others, enhances its effects, especially during illness recovery phases Read Review. One user specifically noted substantial improvements in heart health and overall wellbeing when quercetin was combined with additional vitamins, suggesting a synergistic effect that supports cardiovascular function Read Review.
Moreover, other reviewers have emphasized the benefits of quercetin's antioxidant properties, which reportedly work well with other anti-inflammatory agents, thereby offering a more comprehensive approach to heart health Read Review. Additionally, the combination of quercetin with other supplements appears to improve immune responses and reduce inflammation, factors that contribute to better cardiovascular outcomes Read Review. Overall, user feedback suggests that employing a multi-supplement strategy may provide enhanced support for heart health, particularly in conjunction with quercetin.
Users report that Quercetin is associated with numerous health benefits, particularly for heart health and cardiovascular support. Many reviews highlight its antioxidant and anti-inflammatory properties, which are thought to aid in reducing blood pressure and lowering the risk of atherosclerosis. For instance, one user stated that Quercetin effectively addresses issues such as heart attacks and improves overall blood vessel health Read Review. Additionally, several users noted that regular intake of Quercetin capsules has significantly improved their energy levels and immunity, further contributing to heart health Read Review.
While specific dosage recommendations were not detailed in the reviews, users seem satisfied with the results of their Quercetin supplementation when taken consistently alongside other vitamins such as C and D, and minerals like zinc. This combination appears to enhance Quercetin's overall effectiveness in promoting heart health and reducing inflammation Read Review. Overall, user feedback indicates that Quercetin is considered a beneficial addition to a heart-health regime, but further research and guidance may be needed for precise dosing.
7.5
Supports heart health
2 people found this helpful
Life Extension Quercetin Capsules provide essential support for my health. They aid in enhancing immunity, reducing inflammation, and support heart health. I have experienced greater energy levels and reduced allergy symptoms after consistent use.
7.5
Recovery aid
2 people found this helpful
I ordered quercetin for my father to aid his recovery from Covid. Alongside vitamin D, zinc, and vitamin C, it has been vital in his recuperation process.
7.5
Diverse medical uses
1 people found this helpful
Sumptuously, quercetin has been shown to possess various positive attributes, confirmed by clinical studies. While researchers typically focus on its antioxidant properties, it also offers potential in diverse clinical applications. Quercetin proves effective across several medical fields including allergology, immunology, endocrinology, and oncology. Its antioxidant qualities shield tissues, including the heart, from damage due to oxidative stress.
9
Powerful healing
A good supplement! Quercetin is a powerful antioxidant with significant healing effects on the body. It addresses issues like stroke and heart attack effectively. Its anti-inflammatory properties benefit blood vessels, reduce blood pressure, and protect against atherosclerosis. Additionally, its antioxidant action lowers the risk of cardiovascular disease. Quercetin exhibits strong antitumour effects and may hinder the growth of new cancer cells. I wish you all health and peace!
7.5
Enhances heart function
10 people found this helpful
Quercetin's antioxidant effect combats free radicals and limits oxidation. This natural flavonoid also possesses antihistamine and anti-inflammatory properties that benefit heart function by enhancing the energy supply of cardiomyocytes. I strongly recommend this amazing product!
7.5
Decent results
Quercetin was part of my therapy during the Covid illness and the recovery phase, alongside vitamins C, D, glutathione, resveratrol, zinc, and others. The results have been quite satisfactory!
7.5
Boosts immunity
1 people found this helpful
Life Extension Quercetin capsules have greatly improved my immunity and general health. Quercetin supports heart health, reduces inflammation, and boosts energy. Since starting it regularly, my allergy symptoms have reduced. The packaging is convenient too, making it easier to maintain my wellness.
9
Effective heart protection
Quercetin exerts a myriad of beneficial effects: it is anti-inflammatory, anti-viral, anti-coagulant, and combats oxidation, while also protecting the lungs and heart. It can neutralise vital viral proteins essential for SARS-CoV-2 replication, which, when combined with vitamins and zinc, enhances its efficacy.
9
Quercetin shows promise for heart recovery
Preventive Administration of Quercetin Promotes Survival and Reduces Adverse Ventricular Remodeling after myocardial infarction through facilitating M2-like macrophage polarization.
We investigated how quercetin, a natural compound found in fruits and vegetables, could help prevent damage after a heart attack (myocardial infarction). Our study used adult male mice to analyze the effects of two weeks of quercetin treatment before simulating a heart attack.
The results were encouraging: quercetin improved heart function, enhanced survival rates, and minimized heart damage. Additionally, it appeared to reduce inflammation and increase protective immune responses in the heart. Overall, quercetin shows potential as a helpful player in heart disease recovery.
8
Quercetin shows promise in heart failure
Quercetin improves heart failure by inhibiting cardiomyocyte apoptosis suppressing the MAPK signaling pathway.
We explored how quercetin might help those suffering from heart failure. In our research, we utilized advanced databases to identify specific targets of quercetin, focusing on its effects on heart cells.
Our findings suggest that quercetin may work by reducing cell death in heart cells via the MAPK signaling pathway. Notably, it helped lower a key ratio linked to cell survival and decreased markers of cell stress. Overall, quercetin shows promise in battling heart failure symptoms, but further studies are needed to confirm these effects in broader settings.
9
Quercetin shows heart protection potential
Quercetin Reduces the Susceptibility to Cardiac Reperfusion Arrhythmias in Ovariectomized Rats.
We aimed to understand how quercetin, a natural flavonoid, might help protect against heart issues linked to hormonal changes in postmenopausal conditions. In our study, ovariectomized female rats received either quercetin treatment or a control substance for four weeks.
We found that quercetin significantly reduced heart damage and the risk of abnormal heart rhythms after restoration of blood flow. Additionally, it seemed to support healthier mitochondrial function. Our findings suggest that quercetin could be beneficial in managing heart health during menopause.
8
Quercetin shows heart protection effects
Quercetin protects human coronary artery endothelial cells against hypoxia/reoxygenation-induced mitochondrial apoptosis via the Nrf2/HO-1 axis.
We investigated how quercetin might shield heart cells from damage caused by low oxygen levels. Our study showed that quercetin significantly enhances cell viability and reduces cell death in human coronary artery endothelial cells under stress conditions.
By activating the Nrf2/HO-1 pathway, quercetin helps lower harmful ROS levels and improves mitochondrial function. Importantly, knocking down Nrf2 reduced quercetin's protective effects, highlighting its role in combating oxidative stress and apoptosis. This suggests quercetin could be a promising treatment for coronary heart disease.
8
Quercetin shows promise against heart injury
Quercetin Alleviates LPS-Stimulated Myocardial Injury through Regulating ALOX5/PI3K/AKT Pathway in Sepsis.
This study investigated how quercetin (QUE) affects heart injury linked to sepsis. By mimicking sepsis-induced cardiomyopathy in human heart cells, we found that LPS treatment leads to reduced cell growth and increased injury.
However, QUE showed potential to counter these effects, decreasing cell death and inflammation. Additionally, QUE worked by regulating the ALOX5/PI3K/AKT pathway, indicating a promising role in treating heart conditions related to sepsis.
8
Quercetin improves heart function
Quercetin Ameliorates Myocardial Injury in Diabetic Rats by Regulating Autophagy and Apoptosis through AMPK/mTOR Signaling Pathway.
We explored how quercetin (QUE) impacts heart injuries linked to diabetes in rat models. Using a combination of low-dose streptozotocin and a high-carbohydrate diet, we noticed that diabetic rats showed significant heart damage, which included changes in blood pressure, glucose levels, and heart function.
After treatment with quercetin, improvements in these areas were observed. QUE appeared to encourage heart cell health by promoting cell survival and improving autophagy, a process important for cell maintenance. Overall, quercetin showed potential benefits in heart health for diabetic conditions.
References
Wang L, Lin S, Wei Q, Li T, Mo Q, et al. Preventive Administration of Quercetin Promotes Survival and Reduces Adverse Ventricular Remodeling after myocardial infarction through facilitating M2-like macrophage polarization. Int Immunopharmacol. 2025;151:114296. doi:10.1016/j.intimp.2025.114296
Alam H, Bailing W, Zhao F, Ullah H, Ullah I, et al. An Integrated Network Pharmacology and RNA-seq Approach for Exploring the Protective Effect of Isoquercitrin in Doxorubicin-Induced Cardiotoxicity: Identification of Novel Genes. Cardiovasc Toxicol. 2025;25:541. doi:10.1007/s12012-025-09968-4
Domingos AE, Breves CMDC, Boa LF, de Souza IIA, Maciel L, et al. Quercetin Reduces the Susceptibility to Cardiac Reperfusion Arrhythmias in Ovariectomized Rats. Mol Nutr Food Res. 2025;69:e202400284. doi:10.1002/mnfr.202400284
Long X, Tao S, Yang S, Li S, Rao L, et al. Quercetin improves heart failure by inhibiting cardiomyocyte apoptosis suppressing the MAPK signaling pathway. Nan Fang Yi Ke Da Xue Xue Bao. 2025;45:187. doi:10.12122/j.issn.1673-4254.2025.01.22
Scalise M, Cianflone E, Quercia C, Pagano L, Chiefalo A, et al. Senolytics rejuvenate aging cardiomyopathy in human cardiac organoids. Mech Ageing Dev. 2025;223:112007. doi:10.1016/j.mad.2024.112007
Goshovska Y, Pashevin D, Goncharov S, Lapikova-Bryhinska T, Lisovyi O, et al. Quercetin is a potential therapy for post-infarction NETosis formation. Naunyn Schmiedebergs Arch Pharmacol. 2025;398:5705. doi:10.1007/s00210-024-03602-w
de Oliveira Silva T, Lunardon G, Lino CA, de Almeida Silva A, Zhang S, et al. Senescent cell depletion alleviates obesity-related metabolic and cardiac disorders. Mol Metab. 2025;91:102065. doi:10.1016/j.molmet.2024.102065
Mostafa EMA, Atta R, Maher SA, El-Kherbetawy MK, Ameen AM. Quercetin and its potential therapeutic effects on aluminum phosphide-induced cardiotoxicity in rats: Role of NOX4, FOXO1, ERK1/2, and NF-κB. Tissue Cell. 2024;91:102622. doi:10.1016/j.tice.2024.102622
An W, Tian Q, Guo P, Chen M, Zhang T, et al. Danggui Buxue Decoction and its components dilate coronary artery through activating the inward rectification K channels pathway. J Ethnopharmacol. 2025;338:119064. doi:10.1016/j.jep.2024.119064
Song J, Li S, Zhang B, Wu J, Zhong A. Quercetin protects human coronary artery endothelial cells against hypoxia/reoxygenation-induced mitochondrial apoptosis via the Nrf2/HO-1 axis. Biomed Res. 2024;45:197. doi:10.2220/biomedres.45.197
Guan F, Du H, Li J, Ren H, Dong A. Quercetin Alleviates LPS-Stimulated Myocardial Injury through Regulating ALOX5/PI3K/AKT Pathway in Sepsis. Cardiovasc Toxicol. 2024;24:1116. doi:10.1007/s12012-024-09901-1
Chen Q, Wang J, Sun L, Ba B, Shen D. Mechanism of Astragalus membranaceus (Huangqi, HQ) for treatment of heart failure based on network pharmacology and molecular docking. J Cell Mol Med. 2024;28:e18331. doi:10.1111/jcmm.18331
Chen YF, Qiu Q, Wang L, Li XR, Zhou S, et al. Quercetin Ameliorates Myocardial Injury in Diabetic Rats by Regulating Autophagy and Apoptosis through AMPK/mTOR Signaling Pathway. Am J Chin Med. 2024;52:841. doi:10.1142/S0192415X24500344
Wang X, Xing X, Huang P, Zhang Z, Zhou Z, et al. A Chinese classical prescription Xuefu Zhuyu decoction in the treatment of coronary heart disease: An overview. Heliyon. 2024;10:e28919. doi:10.1016/j.heliyon.2024.e28919
Hu D, Li R, Li Y, Wang M, Wang L, et al. Inflammation-Targeted Nanomedicines Alleviate Oxidative Stress and Reprogram Macrophages Polarization for Myocardial Infarction Treatment. Adv Sci (Weinh). 2024;11:e2308910. doi:10.1002/advs.202308910
Jing J, Fang S, Li Y, Liu W, Wang C, et al. An enhanced cardio-protective effect of nanoparticles loaded with active components from Polygonum orientale L. against isoproterenol-induced myocardial ischemia in rats. Int J Pharm. 2024;655:124047. doi:10.1016/j.ijpharm.2024.124047