Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.4
USERS' SCORE
Good
Based on 11 Reviews
8
Supplement Facts
Serving Size:  1 Vegetarian Capsule
Amount Per Serving
%DV
Vitamin C (from ascorbic acid, camu-camu berry extract)
30 mg
33%
Quercetin (as quercetin dihydrate)
250 mg
**
Optimized Food Blend[onion (bulb) (extracts), bitter orange bioflavonoids (peel and fruit), apple (fruit)
220 mg
**
Camu-camu extract (wildcrafted berry)
50 mg
**

Top Medical Research Studies

We explored how quercetin might help those suffering from heart failure. In our research, we utilized advanced databases to identify specific targets of quercetin, focusing on its effects on heart cells.

Our findings suggest that quercetin may work by reducing cell death in heart cells via the MAPK signaling pathway. Notably, it helped lower a key ratio linked to cell survival and decreased markers of cell stress. Overall, quercetin shows promise in battling heart failure symptoms, but further studies are needed to confirm these effects in broader settings.
Read More
9
Quercetin shows promise for heart recovery
We investigated how quercetin, a natural compound found in fruits and vegetables, could help prevent damage after a heart attack (myocardial infarction). Our study used adult male mice to analyze the effects of two weeks of quercetin treatment before simulating a heart attack.

The results were encouraging: quercetin improved heart function, enhanced survival rates, and minimized heart damage. Additionally, it appeared to reduce inflammation and increase protective immune responses in the heart. Overall, quercetin shows potential as a helpful player in heart disease recovery.
Read More
We aimed to understand how quercetin, a natural flavonoid, might help protect against heart issues linked to hormonal changes in postmenopausal conditions. In our study, ovariectomized female rats received either quercetin treatment or a control substance for four weeks.

We found that quercetin significantly reduced heart damage and the risk of abnormal heart rhythms after restoration of blood flow. Additionally, it seemed to support healthier mitochondrial function. Our findings suggest that quercetin could be beneficial in managing heart health during menopause.
Read More

Most Useful Reviews

9
Powerful healing
A good supplement! Quercetin is a powerful antioxidant with significant healing effects on the body. It addresses issues like stroke and heart attack effectively. Its anti-inflammatory properties benefit blood vessels, reduce blood pressure, and protect against atherosclerosis. Additionally, its antioxidant action lowers the risk of cardiovascular disease. Quercetin exhibits strong antitumour effects and may hinder the growth of new cancer cells. I wish you all health and peace!
Read More
7.5
Supports heart health
2 people found this helpful
Life Extension Quercetin Capsules provide essential support for my health. They aid in enhancing immunity, reducing inflammation, and support heart health. I have experienced greater energy levels and reduced allergy symptoms after consistent use.
Read More
9
Effective heart protection
Quercetin exerts a myriad of beneficial effects: it is anti-inflammatory, anti-viral, anti-coagulant, and combats oxidation, while also protecting the lungs and heart. It can neutralise vital viral proteins essential for SARS-CoV-2 replication, which, when combined with vitamins and zinc, enhances its efficacy.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.4
  • All Researches
9
Quercetin shows promise for heart recovery
We investigated how quercetin, a natural compound found in fruits and vegetables, could help prevent damage after a heart attack (myocardial infarction). Our study used adult male mice to analyze the effects of two weeks of quercetin treatment before simulating a heart attack.

The results were encouraging: quercetin improved heart function, enhanced survival rates, and minimized heart damage. Additionally, it appeared to reduce inflammation and increase protective immune responses in the heart. Overall, quercetin shows potential as a helpful player in heart disease recovery.
Read More
We aimed to understand how quercetin, a natural flavonoid, might help protect against heart issues linked to hormonal changes in postmenopausal conditions. In our study, ovariectomized female rats received either quercetin treatment or a control substance for four weeks.

We found that quercetin significantly reduced heart damage and the risk of abnormal heart rhythms after restoration of blood flow. Additionally, it seemed to support healthier mitochondrial function. Our findings suggest that quercetin could be beneficial in managing heart health during menopause.
Read More
We explored how senolytics, specifically dasatinib and quercetin, can rejuvenate aging heart muscle cells. By modeling doxorubicin-induced cardiomyopathy in human cardiac organoids, we treated these aged cells with the senolytics after they exhibited age-related damage.

Our findings showed that this treatment reduced oxidative stress and cellular damage, improving cell function and structure. Overall, senolytics were effective in restoring the viability and regenerative capabilities of these heart cells, highlighting their potential for treating age-related heart conditions.
Read More
We explored whether quercetin could help reduce heart damage following a heart attack. In our study, Wistar rats underwent a procedure simulating a heart attack and received quercetin before the reperfusion phase. The results were encouraging—quercetin treatment improved heart function and reduced the formation of harmful substances called NETs. This suggests that quercetin may be a valuable tool for protecting the heart during recovery from cardiac events. However, our findings mainly apply to animal models and require further research in humans for validation.
Read More
9
DBD components help coronary dilation
We explored how Danggui Buxue Decoction (DBD) and its ingredients, such as quercetin, influence coronary artery dilation. By examining pre-constricted coronary arteries in a lab setting with rats, we found that the active components of DBD effectively activated potassium channels, leading to increased blood flow in the coronary arteries.

While DBD shows promise for treating conditions like coronary heart disease, more research is needed to fully understand the mechanisms behind its effects. Overall, our findings suggest it could be a beneficial therapy for those suffering from vascular issues.
Read More

User Reviews

USERS' SCORE
Good
Based on 11 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Powerful healing
A good supplement! Quercetin is a powerful antioxidant with significant healing effects on the body. It addresses issues like stroke and heart attack effectively. Its anti-inflammatory properties benefit blood vessels, reduce blood pressure, and protect against atherosclerosis. Additionally, its antioxidant action lowers the risk of cardiovascular disease. Quercetin exhibits strong antitumour effects and may hinder the growth of new cancer cells. I wish you all health and peace!
Read More
7.5
Supports heart health
2 people found this helpful
Life Extension Quercetin Capsules provide essential support for my health. They aid in enhancing immunity, reducing inflammation, and support heart health. I have experienced greater energy levels and reduced allergy symptoms after consistent use.
Read More
9
Effective heart protection
Quercetin exerts a myriad of beneficial effects: it is anti-inflammatory, anti-viral, anti-coagulant, and combats oxidation, while also protecting the lungs and heart. It can neutralise vital viral proteins essential for SARS-CoV-2 replication, which, when combined with vitamins and zinc, enhances its efficacy.
Read More
7.5
Reduces risk
Quercetin possesses robust antioxidant qualities. Numerous studies indicate that it can reduce the risk of atherosclerosis, prevent cardiovascular disease, and lower blood pressure. In this formulation, quercetin is paired with vitamin C, enhancing its effects.
Read More
7.5
Decent results
Quercetin was part of my therapy during the Covid illness and the recovery phase, alongside vitamins C, D, glutathione, resveratrol, zinc, and others. The results have been quite satisfactory!
Read More

Frequently Asked Questions

7.5
Supports heart health
2 people found this helpful
Life Extension Quercetin Capsules provide essential support for my health. They aid in enhancing immunity, reducing inflammation, and support heart health. I have experienced greater energy levels and reduced allergy symptoms after consistent use.
7.5
Recovery aid
2 people found this helpful
I ordered quercetin for my father to aid his recovery from Covid. Alongside vitamin D, zinc, and vitamin C, it has been vital in his recuperation process.
7.5
Diverse medical uses
1 people found this helpful
Sumptuously, quercetin has been shown to possess various positive attributes, confirmed by clinical studies. While researchers typically focus on its antioxidant properties, it also offers potential in diverse clinical applications. Quercetin proves effective across several medical fields including allergology, immunology, endocrinology, and oncology. Its antioxidant qualities shield tissues, including the heart, from damage due to oxidative stress.
9
Powerful healing
A good supplement! Quercetin is a powerful antioxidant with significant healing effects on the body. It addresses issues like stroke and heart attack effectively. Its anti-inflammatory properties benefit blood vessels, reduce blood pressure, and protect against atherosclerosis. Additionally, its antioxidant action lowers the risk of cardiovascular disease. Quercetin exhibits strong antitumour effects and may hinder the growth of new cancer cells. I wish you all health and peace!
7.5
Enhances heart function
10 people found this helpful
Quercetin's antioxidant effect combats free radicals and limits oxidation. This natural flavonoid also possesses antihistamine and anti-inflammatory properties that benefit heart function by enhancing the energy supply of cardiomyocytes. I strongly recommend this amazing product!
7.5
Decent results
Quercetin was part of my therapy during the Covid illness and the recovery phase, alongside vitamins C, D, glutathione, resveratrol, zinc, and others. The results have been quite satisfactory!
7.5
Boosts immunity
1 people found this helpful
Life Extension Quercetin capsules have greatly improved my immunity and general health. Quercetin supports heart health, reduces inflammation, and boosts energy. Since starting it regularly, my allergy symptoms have reduced. The packaging is convenient too, making it easier to maintain my wellness.
9
Effective heart protection
Quercetin exerts a myriad of beneficial effects: it is anti-inflammatory, anti-viral, anti-coagulant, and combats oxidation, while also protecting the lungs and heart. It can neutralise vital viral proteins essential for SARS-CoV-2 replication, which, when combined with vitamins and zinc, enhances its efficacy.
9
Quercetin shows promise for heart recovery
We investigated how quercetin, a natural compound found in fruits and vegetables, could help prevent damage after a heart attack (myocardial infarction). Our study used adult male mice to analyze the effects of two weeks of quercetin treatment before simulating a heart attack.

The results were encouraging: quercetin improved heart function, enhanced survival rates, and minimized heart damage. Additionally, it appeared to reduce inflammation and increase protective immune responses in the heart. Overall, quercetin shows potential as a helpful player in heart disease recovery.
We explored how quercetin might help those suffering from heart failure. In our research, we utilized advanced databases to identify specific targets of quercetin, focusing on its effects on heart cells.

Our findings suggest that quercetin may work by reducing cell death in heart cells via the MAPK signaling pathway. Notably, it helped lower a key ratio linked to cell survival and decreased markers of cell stress. Overall, quercetin shows promise in battling heart failure symptoms, but further studies are needed to confirm these effects in broader settings.
We aimed to understand how quercetin, a natural flavonoid, might help protect against heart issues linked to hormonal changes in postmenopausal conditions. In our study, ovariectomized female rats received either quercetin treatment or a control substance for four weeks.

We found that quercetin significantly reduced heart damage and the risk of abnormal heart rhythms after restoration of blood flow. Additionally, it seemed to support healthier mitochondrial function. Our findings suggest that quercetin could be beneficial in managing heart health during menopause.
8
Quercetin shows heart protection effects
We investigated how quercetin might shield heart cells from damage caused by low oxygen levels. Our study showed that quercetin significantly enhances cell viability and reduces cell death in human coronary artery endothelial cells under stress conditions.

By activating the Nrf2/HO-1 pathway, quercetin helps lower harmful ROS levels and improves mitochondrial function. Importantly, knocking down Nrf2 reduced quercetin's protective effects, highlighting its role in combating oxidative stress and apoptosis. This suggests quercetin could be a promising treatment for coronary heart disease.
8
Quercetin shows promise against heart injury
This study investigated how quercetin (QUE) affects heart injury linked to sepsis. By mimicking sepsis-induced cardiomyopathy in human heart cells, we found that LPS treatment leads to reduced cell growth and increased injury.

However, QUE showed potential to counter these effects, decreasing cell death and inflammation. Additionally, QUE worked by regulating the ALOX5/PI3K/AKT pathway, indicating a promising role in treating heart conditions related to sepsis.
8
Quercetin improves heart function
We explored how quercetin (QUE) impacts heart injuries linked to diabetes in rat models. Using a combination of low-dose streptozotocin and a high-carbohydrate diet, we noticed that diabetic rats showed significant heart damage, which included changes in blood pressure, glucose levels, and heart function.

After treatment with quercetin, improvements in these areas were observed. QUE appeared to encourage heart cell health by promoting cell survival and improving autophagy, a process important for cell maintenance. Overall, quercetin showed potential benefits in heart health for diabetic conditions.

References

  1. Wang L, Lin S, Wei Q, Li T, Mo Q, et al. Preventive Administration of Quercetin Promotes Survival and Reduces Adverse Ventricular Remodeling after myocardial infarction through facilitating M2-like macrophage polarization. Int Immunopharmacol. 2025;151:114296. doi:10.1016/j.intimp.2025.114296
  2. Alam H, Bailing W, Zhao F, Ullah H, Ullah I, et al. An Integrated Network Pharmacology and RNA-seq Approach for Exploring the Protective Effect of Isoquercitrin in Doxorubicin-Induced Cardiotoxicity: Identification of Novel Genes. Cardiovasc Toxicol. 2025;25:541. doi:10.1007/s12012-025-09968-4
  3. Domingos AE, Breves CMDC, Boa LF, de Souza IIA, Maciel L, et al. Quercetin Reduces the Susceptibility to Cardiac Reperfusion Arrhythmias in Ovariectomized Rats. Mol Nutr Food Res. 2025;69:e202400284. doi:10.1002/mnfr.202400284
  4. Long X, Tao S, Yang S, Li S, Rao L, et al. Quercetin improves heart failure by inhibiting cardiomyocyte apoptosis suppressing the MAPK signaling pathway. Nan Fang Yi Ke Da Xue Xue Bao. 2025;45:187. doi:10.12122/j.issn.1673-4254.2025.01.22
  5. Scalise M, Cianflone E, Quercia C, Pagano L, Chiefalo A, et al. Senolytics rejuvenate aging cardiomyopathy in human cardiac organoids. Mech Ageing Dev. 2025;223:112007. doi:10.1016/j.mad.2024.112007
  6. Goshovska Y, Pashevin D, Goncharov S, Lapikova-Bryhinska T, Lisovyi O, et al. Quercetin is a potential therapy for post-infarction NETosis formation. Naunyn Schmiedebergs Arch Pharmacol. 2025;398:5705. doi:10.1007/s00210-024-03602-w
  7. de Oliveira Silva T, Lunardon G, Lino CA, de Almeida Silva A, Zhang S, et al. Senescent cell depletion alleviates obesity-related metabolic and cardiac disorders. Mol Metab. 2025;91:102065. doi:10.1016/j.molmet.2024.102065
  8. Mostafa EMA, Atta R, Maher SA, El-Kherbetawy MK, Ameen AM. Quercetin and its potential therapeutic effects on aluminum phosphide-induced cardiotoxicity in rats: Role of NOX4, FOXO1, ERK1/2, and NF-κB. Tissue Cell. 2024;91:102622. doi:10.1016/j.tice.2024.102622
  9. An W, Tian Q, Guo P, Chen M, Zhang T, et al. Danggui Buxue Decoction and its components dilate coronary artery through activating the inward rectification K channels pathway. J Ethnopharmacol. 2025;338:119064. doi:10.1016/j.jep.2024.119064
  10. Song J, Li S, Zhang B, Wu J, Zhong A. Quercetin protects human coronary artery endothelial cells against hypoxia/reoxygenation-induced mitochondrial apoptosis via the Nrf2/HO-1 axis. Biomed Res. 2024;45:197. doi:10.2220/biomedres.45.197
  11. Guan F, Du H, Li J, Ren H, Dong A. Quercetin Alleviates LPS-Stimulated Myocardial Injury through Regulating ALOX5/PI3K/AKT Pathway in Sepsis. Cardiovasc Toxicol. 2024;24:1116. doi:10.1007/s12012-024-09901-1
  12. Chen Q, Wang J, Sun L, Ba B, Shen D. Mechanism of Astragalus membranaceus (Huangqi, HQ) for treatment of heart failure based on network pharmacology and molecular docking. J Cell Mol Med. 2024;28:e18331. doi:10.1111/jcmm.18331
  13. Chen YF, Qiu Q, Wang L, Li XR, Zhou S, et al. Quercetin Ameliorates Myocardial Injury in Diabetic Rats by Regulating Autophagy and Apoptosis through AMPK/mTOR Signaling Pathway. Am J Chin Med. 2024;52:841. doi:10.1142/S0192415X24500344
  14. Wang X, Xing X, Huang P, Zhang Z, Zhou Z, et al. A Chinese classical prescription Xuefu Zhuyu decoction in the treatment of coronary heart disease: An overview. Heliyon. 2024;10:e28919. doi:10.1016/j.heliyon.2024.e28919
  15. Hu D, Li R, Li Y, Wang M, Wang L, et al. Inflammation-Targeted Nanomedicines Alleviate Oxidative Stress and Reprogram Macrophages Polarization for Myocardial Infarction Treatment. Adv Sci (Weinh). 2024;11:e2308910. doi:10.1002/advs.202308910
  16. Jing J, Fang S, Li Y, Liu W, Wang C, et al. An enhanced cardio-protective effect of nanoparticles loaded with active components from Polygonum orientale L. against isoproterenol-induced myocardial ischemia in rats. Int J Pharm. 2024;655:124047. doi:10.1016/j.ijpharm.2024.124047
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